fentanyl iontophoretic transdermal program and butabarbital each increase sedation. Avoid or Use Alternate Drug. Restrict use to clients for whom different therapy choices are inadequate
In the event you miss out on a dose, consider it once you could. If it is nearly time for your up coming dose, just take only that dose. Don't get double or further doses.
Dosage adjustment for concomitant therapy: Significant drug interactions exist, demanding dose/frequency adjustment or avoidance. Seek the advice of drug interactions databases To find out more.
These agents must only be mixed if different remedy possibilities are inadequate. If combined, limit the dosages and period of each and every drug. Take into account therapy modification
butabarbital will reduce the extent or impact of dexamethasone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
Brainstem reflexes ended up absent right until pentobarbital concentrations fell substantially, reminding clinicians to be careful When contemplating the prognosis of brain death pursuing drug overdose.
butabarbital will lower the extent or result of pimozide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Mysterious.
butabarbital will lower the extent or influence of quinine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
butabarbital will reduce the level or outcome of ramelteon by affecting hepatic enzyme CYP2C9/ten metabolism. Slight/Significance Not known.
In Extraordinary overdose, all electrical activity inside the brain may possibly stop, in which scenario a “flat” EEG normally equated with scientific death can not be acknowledged.
butabarbital will lower the extent or effect of alfentanil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unidentified.
butabarbital will minimize the level or more info influence of dapsone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unfamiliar.
butabarbital and olopatadine intranasal both equally enhance sedation. Prevent or Use Alternate Drug. Coadministration increases possibility of CNS melancholy, which may result in additive impairment of psychomotor general performance and induce daytime impairment.
butabarbital will lessen the extent or impact of etoposide by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.